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Device to slow down Alzheimer’s disease

By HERWriter
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New research suggests a ‘brain pacemaker’ may slow the progression of Alzheimer’s disease. In a small study, Johns Hopkins University scientists found a device that sends electrical impulses to the brain’s memory regions appeared to increase neuron activity in patients who were suspected to have the disease.

The researchers implanted the device in six people with mild or early-stage Alzheimer’s disease. The device includes electrodes, which are implanted in the brain, and a pacemaker, which is implanted in the chest, connected to the electrodes by wires. The pacemaker orders the electrodes to continuously stimulate the brain. This technique is known as deep brain stimulation, or DBS.

A year after implanting the device, the researchers conducted PET scans on the patients and found they actually showed an increase of glucose metabolism, which the brain uses as fuel to function. Greater amounts of glucose metabolism also indicate greater amounts of brain cell activity, according to the researchers.

“In the regular course of Alzheimer’s, glucose metabolism is decreased and a widespread network of brain regions are affected,” the study’s first author Gwen Smith, a professor in the Department of Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine, told FoxNews.com.

“We find that increases in glucose metabolism lead to improvements in brain function correlated with behaviors – so patients with greater increases had better clinical outcomes in Alzheimer’s disease as far as keeping the disease where it is, and keeping it stable,” Smith added.

DBS has previously been used in the treatment of Parkinson’s disease and depression. To treat Parkinson’s, the device targets the motor regions rather than stimulating the brain’s memory regions.

According to Smith, the idea to use DBS to treat Alzheimer’s came about when Dr. Andres Lozano, the lead researcher of the study and chairman of the Department of Neurosurgery at the University of Toronto, used the treatment on an obese man to target regions in the brain related to appetite suppression.

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

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