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The Progression of Alzheimer's Disease and Factors That Influence It

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Patients may have changes to their brain years before they receive a diagnosis of Alzheimer's disease. The Alzheimer's Association explains that these neurological changes may start 20 or more years before a doctor give a patient the diagnosis of early-stage Alzheimer's disease. Alzheimer's disease causes multiple changes to the brain, such as changes in structure size and formation of plaques and tangles. But how does Alzheimer's disease progress?

The Alzheimer's Association lays out seven stages of Alzheimer's disease. As a patient progresses through each stage of Alzheimer's disease, the impairment becomes worse. For example, in stage one of Alzheimer's disease, the patient has normal function. When she reaches stage two, or mild cognitive decline, she may start having memory lapses, though this may be due to age. With stage three of Alzheimer's disease, the patient develops mild cognitive decline, which affects her ability to remember names, plan or learn new materials through reading.

By stage four of Alzheimer's disease, or moderate cognitive decline, the patient is showing several identifiable problems. For example, the patient may not be able to do challenging arithmetic in her head, such as counting backwards from the number 100 by groups of seven. The memory problems have worsened to affect the patient's memory of her own life. Changes in personality and mood occur, such as becoming withdrawn or having mood swings. In the last three stages of Alzheimer's disease, the cognitive impairment is severely worse. For example, in stage five of Alzheimer's disease, the patient cannot remember her address or telephone number. In stage six of Alzheimer's disease, the patient has trouble remembering the name of her spouse or caregiver. By the last stage of Alzheimer's disease, the patient needs help to carry out basic survival tasks.

Can certain factors affect the progression of Alzheimer's disease?

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EmpowHER Guest

Elizabeth, this is a very nice article that clearly describes the different challenges caregivers have as Alzheimer's progresses. I wanted to share an article with your readers that was written by a colleague of mine that complements your article. Her article is called "Understand Alzheimer's Disease in 3 Minutes." It has a very good animated video that shows the damage to the brain as disease moves through the stages.

October 13, 2010 - 2:33pm
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