Vitamin B6 Therapy for Carpal Tunnel Syndrome

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There have been some studies that suggest that taking a vitamin B6 supplement can stop or reduce the symptoms of carpal tunnel syndrome, although this evidence is inconclusive.

Vitamin B6 is needed for a variety of functions. It helps with the formulation of red blood cells, the healthy functioning of the nervous system and immune system, correct metabolism, and the production of serotonin which helps guard against depression and other mental disorders. Pregnant women can sometimes alleviate morning sickness with vitamin B6.

Some research has shown vitamin B6 to be an effective treatment for carpal tunnel syndrome. For instance, a study in Spain showed that six patients had clinical improvement and increased nerve function after supplementation:

"Patients were treated with 150 mg of pyridoxine (B6) daily for three months. In six patients there were clinical and electrophysiological improvement and erythrocyte aspartate aminotransferase increased more than in the other six patients. The data obtained appear to indicate that although vitamin B6 deficiency is not common in carpal tunnel syndrome patients, pyridoxine supplementation can be recommended as adjuvant treatment in those patients undergoing surgery."

An older study found that not only did vitamin B6 resolve the symptoms of carpal tunnel syndrome, but it was apparent that in some cases, the syndrome was caused by a vitamin B6 deficiency.

"Clinical evaluation was made of cross-over treatments by pyridoxine and a placebo of patient 22 having the carpal tunnel syndrome. On placebo, both the vitamin B6 deficiency and syndrome reappeared. Retreatment with 100 mg again corrected both the deficiency and syndrome. Scores of 17 symptoms revealed reductions at both the 2- and 100-mg dosages. Conduction through the carpal tunnels had improved by electromyography. These and previous data on a total of 22 patients showed the concomitant presence of a deficiency of vitamin B6 and the carpal tunnel syndrome; a causal relationship is apparent."

Side-Effects:

The recommended daily intake of vitamin B6 is only 1.3mgs for adults and 1.9mgs for pregnant adults but this is the bare minimum of what is necessary for human health and 2 percent of the population will not find this enough. Some conditions would necessitate more vitamin B6.

Dosages of 100mgs or more have been used successfully in the treatment of a variety of illnesses. Occasionally, taking too much B6 can cause neuropathies and numbness and tingling similar to that of carpal tunnel syndrome. A journal reported motor and sensory neuropathy overdose of vitamin B6:

"An 81-year-old woman was admitted to the hospital because of difficulty in walking and frequent falls. History revealed that she had been taking large doses of pyridoxine daily for several months as treatment for carpal tunnel syndrome. Diagnostic work-up failed to suggest a cause for her symptoms. Nerve conduction studies revealed slowing of motor conduction velocities, prolonged F wave latencies, and prolonged sensory latencies in both lower extremities. We believe the patient's complaints and the results of nerve conduction studies were secondary to pyridoxine neurotoxicity."

However, side-effects are not normally reported in doses less than 500mgs daily so it is very unlikely you will have any problems if you take around 100mgs a day. If you are pregnant or have a complicated medical condition, please tell your health care provider you are taking this vitamin.

Sources: Klin Wochenschr. 1989 Jan 4;67(1):38-41, Am J Clin Nutr. 1979 Oct;32(10):2040-6, Arch Phys Med Rehabil. 1985 Sep;66(9):634-6.

Joanna is a freelance health writer for The Mother magazine and Suite 101 with a column on infertility, http://infertility.suite101.com/. She is author of the book, 'Breast Milk: A Natural Immunisation,' and co-author of an educational resource on disabled parenting, in addition to running a charity for people damaged by vaccines or medical mistakes.

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.