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What is Fibrous Dysplasia?

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Bones & Joints related image Photo: Getty Images

When scar-like tissue develops instead of normal bone, this is a disorder known as fibrous dysplasia. This tissue will expand as the bone grows, causing the bone to weaken. This can then cause the bone to become deformed and therefore more likely to fracture in the event of a fall or injury.

When one is affected with a mild case of this bone disorder, it may not always create signs or symptoms. The more serious cases can contribute to bone pain and deformity, usually beginning before the individual is 15 years of age.

No exact cause for fibrous dysplasia is known at this time, and as there is no cure, the emphasis of treatment is to relieve the signs and symptoms.

Although fibrous dysplasia can occur in any bone in the body, most people afflicted with this condition have only one bone affected. When this disease affects just one bone, it is referred to as monostotic fibrous dysplasia. When it affects more than one bone, it is called polystotic fibrous dysplasia.

The bones in the body that are usually affected by this condition include the thighbone, the shinbone, the bones in the pelvic region, the ribs, the skull, bones in the face, and the upper arm bone.

If fibrous dysplasia is affecting more than one bone in the body, the symptoms may include bone pain, difficulty walking, deformities in the bone(s), and fractures. Although rare, it can cause abnormalities in the glands of the endocrine system that are responsible for producing hormones, which can contribute to an early onset of puberty, problems with the thyroid glands, or discoloration of the skin.

Fibrous dysplasia develops before birth and has been linked to a gene mutation that affects the cells produced by the bones. While the cause for such mutation is not known or understood, it is not an inherited disease, nor one that you can pass on to your children.

Since bones are living tissue, they are always actively at work, even after you stop growing. As they work to remodel themselves, bone cells known as osteoclasts work to tear down the old bone while osteoblasts work to rebuild new bone. It’s a constant process.

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.