NO/ONOO Cycle May be Cause of CFS, MCS and FM

By Jody Smith HERWriter
 
Rate This

What do Chronic Fatigue Syndrome (CFS), multiple chemical sensitivities (MCS) and fibromyalgia (FM) all have in common?

According to Martin Pall, Professor Emeritus of Biochemistry and Basic Medical Science at Washington State University, they may all be caused by a biochemical cycle dubbed the NO/ONOO cycle.

"Previous studies have shown that agents that lower such cycle elements as oxidative stress, nitric oxide, inflammatory responses, mitochondrial dysfunction, tetrahydrobiopterin (BH4) depletion and NMDA activity produce clinical improvements in CFS/ME and FM patients, consistent with the predictions of the cycle mechanism."

The February/ March edition of The Townsend Letter: The Examiner of Alternative Medicine published Pall's paper "How Can We Cure NO/ONOO-Cycle Diseases? Approaches to Curing Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, Fibromyalgia, Multiple Chemical Sensitivity, Gulf War Syndrome and Possibly Many Others".

Another paper written by Pall, "Multiple Chemical Sensitivity: Toxicological Questions and Mechanisms" was published in General and Applied Toxicology, 3rd Edition, an important work for professional toxicologists.

http://www.thecanaryreport.org/category/research-mcs

Add a CommentComments

There are no comments yet. Be the first one and get the conversation started!

Image CAPTCHA
Enter the characters shown in the image.
By submitting this form, you agree to EmpowHER's terms of service and privacy policy

We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

Chronic Fatigue Syndrome

Get Email Updates

Health Newsletter

Receive the latest and greatest in women's health and wellness from EmpowHER - for free!

Improved

3312 Health

Changed

2037 Lives

Saved

1894 Lives
7 lives impacted in the last 24 hrs Learn More

Take Our Featured Health Poll

Have you joined the IUD trend? What kind of birth control do you use? :
View Results