Facebook Pixel

Gum Disease: Risk for Kidney Failure

Rate This

Chronic kidney disease is widespread and often undiagnosed. Estimates of its prevalence in the U.S. population are as high as 13%. The National Kidney Foundation describes 5 stages, from mild impairment to kidney failure requiring dialysis or transplant. Early detection and treatment can prevent progression of the disease to this stage in many cases. But in up to 75% of chronic kidney disease cases, the patient has no warning until drastic treatment measures are necessary.

Early warning signs of kidney dysfunction could improve the lives of millions of Americans. A research group at Case Western Reserve University hypothesized that periodontal (gum) disease could be one of the red flags. The systemic inflammatory response of the body to gum disease is associated with changes in several medical conditions, including heart disease, osteoporosis, diabetes, respiratory conditions, and pregnancy. See


The Case Western researchers studied 12,947 adults from the Third National Health and Nutrition Examination Survey. They found that subjects with periodontal disease were twice as likely to have chronic kidney disease as subjects with healthy gums, after adjusting for other traditional and non-traditional risk factors.

Periodontal disease was defined for this study as one or more sites with a loss of attachment of at least 4 mm and bleeding on the same tooth. In the most severe cases, the patient loses all his or her natural teeth, and is then defined as edentulous.

The risk for chronic kidney failure is greater for more severe cases of periodontal disease, independent of the person's overall health. The mechanism for this association is not completely understood, but the results are clear. Kidney failure is a major concern for both public health issues and individual quality of life. Any tool we can use to identify individuals at risk has potential to reduce the numbers of dialysis and transplant patients.

by Linda Fugate, Ph.D.


Add a Comment2 Comments

Thank you for this additional information. I am never far from my dental floss!

August 25, 2009 - 6:24am

According to the American Academy of Periodontology, there is a correlation between gum health and chronic inflammatory conditions, such as diabetes, cardiovascular disease and Alzheimer’s disease.

Learn more about Periodontitis

August 24, 2009 - 6:48pm
Enter the characters shown in the image.
By submitting this form, you agree to EmpowHER's terms of service and privacy policy
Add a Comment

We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

Chronic Kidney Disease

Get Email Updates

Chronic Kidney Disease Guide


Have a question? We're here to help. Ask the Community.


Health Newsletter

Receive the latest and greatest in women's health and wellness from EmpowHER - for free!