Take unused, unneeded, or expired prescription drugs out of their original containers and throw them in the trash.
Mixing prescription drugs with an undesirable substance, such as used coffee grounds or kitty litter, and putting them in impermeable, non-descript containers, such as empty cans or sealable bags, will further ensure the drugs are not diverted.
Flush prescription drugs down the toilet only if the label or accompanying patient information specifically instructs doing so.
Take advantage of community pharmaceutical take-back programs that allow the public to bring unused drugs to a central location for proper disposal. Some communities have pharmaceutical take-back programs or community solid-waste programs that allow the public to bring unused drugs to a central location for proper disposal. Where these exist, they are a good way to dispose of unused pharmaceuticals.
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You're wise to question the best methods for disposing of expired prescription drugs - for that matter, even OTC drugs. The Office of National Drug Control Policy published these Federal Guidelines:
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