Antidepressants are highly effective in a variety of pain syndromes. They are known to be effective in alleviating cancer pain, alone, or in potentiating narcotics. And we know why: prostaglandins have a significant role in cancer, in inflammation, and in pain, and antidepressants block prostaglandins. In all of the recent discussions of chronic post-mastectomy pain, I could not find one reference to the use of antidepressants.
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Antidepressants are highly effective in a variety of pain syndromes. They are known to be effective in alleviating cancer pain, alone, or in potentiating narcotics. And we know why: prostaglandins have a significant role in cancer, in inflammation, and in pain, and antidepressants block prostaglandins. In all of the recent discussions of chronic post-mastectomy pain, I could not find one reference to the use of antidepressants.
December 12, 2009 - 7:41amThis Comment
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