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(reply to Cary Cook BSN RN)

Hi, Cary,

Hmmm... I'm wondering where you got your information that baclofen, "can cause central nervous system depression and syncope, so large doses can be dangerous." I've done a lot of reading about high-dosage baclofen and this is the first time I've read about these side effects. What I have read is that baclofen has been used for decades and is still being used at high doses (up to 300mg/day) for MS patients with only minor side effects. Can you direct me to credible, medical references that back your statement?

Thanks.

Bob

June 22, 2011 - 8:00pm

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