Seminiferous tubule dysgenesis is the only cause of Klinefelter's syndrome, as the word 'syndrome' means 'a collection of symptoms indicative of disease' there has to be a disease that causes it, stands to reason, if you think about it?
XXY foetuses, infants, children before puberty can't have Klinefelter's syndrome as the testes are not diseased until after the onset of puberty in males with some degree of additional X genetic material, in their testes. It is quite conceivable that a male with the additional X in his white blood cells, has none in his testes, therefore he will not develop the symptoms of the disease, as he won't have the disease.
It is just laziness of the medical professions to say all XXY males at whatever stage of life have Klinefelter's syndrome.
XXY and Klinefelter's syndrome are not the same thing.
Such as what symptoms of disease are XXX females known by? What symptoms of disease are XYY males known by? What symptoms of disease are Fragile X people known by? The answer is NONE for ALL. It is simply because symptoms of disease were described before the karyotype was discovered that the symptoms of disease became the primary focus.
I encourage people to think KARYOTYPE not SYMPTOMS of DISEASE when considering actions regarding results of prenatal testing for XXY
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Seminiferous tubule dysgenesis is the only cause of Klinefelter's syndrome, as the word 'syndrome' means 'a collection of symptoms indicative of disease' there has to be a disease that causes it, stands to reason, if you think about it?
XXY foetuses, infants, children before puberty can't have Klinefelter's syndrome as the testes are not diseased until after the onset of puberty in males with some degree of additional X genetic material, in their testes. It is quite conceivable that a male with the additional X in his white blood cells, has none in his testes, therefore he will not develop the symptoms of the disease, as he won't have the disease.
It is just laziness of the medical professions to say all XXY males at whatever stage of life have Klinefelter's syndrome.
XXY and Klinefelter's syndrome are not the same thing.
Such as what symptoms of disease are XXX females known by? What symptoms of disease are XYY males known by? What symptoms of disease are Fragile X people known by? The answer is NONE for ALL. It is simply because symptoms of disease were described before the karyotype was discovered that the symptoms of disease became the primary focus.
I encourage people to think KARYOTYPE not SYMPTOMS of DISEASE when considering actions regarding results of prenatal testing for XXY
August 11, 2013 - 6:10pmThis Comment
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