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hey thanks for you assistance
April 28, 2013 - 4:15amMy bone marrow test was: 20 cells were analyzed 10 were positive for Philadelphia and 10 were negative.. so i am taking glivec for last 5 months why the situation is?/ and my next question is that my bcr-abl was 97% while 500cells was analyzed plz i am worrying about this situation.. coz i have used glivec for 5 months and is this response of drug enough or not ... or what i should do further.. may i change my tablets to tasignia or what should i do plz
This Comment
Hi Arshad, May I know where are you from? I am from Bombay, India. Six months back even I was Diagnose with cml and I am taking Dasatinib 100 mg medicine since then. My cbc count were in control with in a month and then my abl-BCR/ PCR was also 1.97% in 3 months. May be you need to find good doctor. It is important that you stay positive and clam for medicines to react positive.
May 9, 2013 - 9:49pmHi Arshad - If you are saying your BCR-ABL is 97% after five months of treatment, and you have been sure to take your medication every single day, then that most likely means your treatment, Glivec, is not working for you.
April 28, 2013 - 8:16amYour next steps need to be determined by a hematologist/oncologist who may want to do another bone marrow biopsy and also a mutations test to better understand the state of your disease and which treatment would be the right one for you. There are five other options in addition to Glivec today so the chances are good that you will find the one that is right for you. They are stronger and address different mutations. In an earlier message you said you were diagnosed in the accelerated phase, that could mean that a transplant would be the right treatment for you. Those are rarely done today but are still done for CML in some cases when it is clear that drug therapy will not be able to help the patient.
There is much reason to have hope, but it is important to work with a doctor who really understands CML and can give you the best care. If you have to travel to get to the right doctor then I would do so. Your life is too important, right? Good luck to you! Pat
i have normal c.b.c now my platelets are in normal range and also my tlc is normal but my doctor still told me that you take 600 mg gleveec and he said me that you are in acceleration phase why he told me... once my platete rate was increased but i have normal c.b.c now plz inform me as soon as possible
February 9, 2013 - 7:15amFirst, patients with CML take medication for the rest of their lives. The CML drugs stop the production of leukemia cells and if patients stop taking the drugs the disease is not being treated. Stopping medication will move the disease from the initial or chronic phase to the advanced or accelerated phase. It is absolutely critical to take CML medication every day and exactly as prescribed to remain healthy.
Second, a CBC does not measure or indicate the state of CML. This is done through a bone marrow biopsy and PCR testing. Please see this website to better understand PCR. http://www.whatismypcr.org/
February 14, 2013 - 2:28pmHi, I want to know what is the time frame to continue with the medication for a CML phase. Do I have to consume the Imatinib as long as I leave or there is a specific duration for the same.
February 2, 2013 - 9:57amCurrently CML medications are taken for the rest of a patient's life. Over time a patient can lose response to a specific medication so ongoing monitoring to be sure the medication is continuing to work is necessary and if the medication is no longer working than a new one will be needed. Ongoing clinical trials are underway to determine if one day it will be possible to take the medication for shorter periods and maintain response, but the data is not clear at this time.
February 2, 2013 - 10:13ammy doctor recomment me jak 2 mutation...why he recomment it ..
January 7, 2013 - 7:59amArshad - Your question is not clear. I' m guessing your doctor has ordered a test for the JAK 2 mutation. The test may be ordered as a follow-up when there's an increased hemoglobin and/or platelet count to determine if determine if a patient has a myeloproliferative disorder and for other reasons. http://labtestsonline.org/understanding/analytes/jak2/tab/test
January 15, 2013 - 12:26pmYou should discuss this with your doctor and get more information.
Pat
how many years can a cml patient live alive?
December 4, 2012 - 5:42am