Hi I am on Letrozole 5mg this month for fertility and having bad cramps and bloating and feeling on and off nauseated for 2 days now. I am on day 22 of my 28 day cycle. What could this be from?

My stomach and face are so bloated since i started taking letrozole. The nausea and fatigue have finally simmered down, started on my 3rd month. I do have a few minor body aches and major insomnia and hot flashes. I'm glad I'm not the only one bloating.

Hi Mellor,

Thank you for your question and welcome to EmpowHer!

The symptoms you are experiencing are a result of Letrozele. Nausea, stomach pains, and water retention (which will lead to bloating) are all common side effects of the medication.

Other common side effects include: Back, leg, or arm pain; breast pain; constipation; cough; diarrhea; dizziness; headache; hot flashes; flushing; increased sweating; indigestion; joint or muscle pain; loss of appetite; mild swelling or fluid retention; nausea; night sweats; sleeplessness; stomach pain; tiredness; vaginal dryness or irritation; vomiting; weakness; weight gain or loss.

More serious side effects that require medical attention include: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); calf pain or tenderness; chest pain; confusion; fever, chills, or sore throat; increased or painful urination; numbness of an arm or leg; one-sided weakness; severe or persistent bone pain; severe stomach pain; shortness of breath; sudden severe headache, vomiting, dizziness, or fainting; swelling of the ankles or feet; unexplained vaginal bleeding or discharge; vision or speech changes.

Hope this helps,

Rosa