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I've been on Premarin for 32 years due to complete hysterectomy at age 32. I'm now 64. Can I ease off of this medication safely?

By Anonymous June 6, 2016 - 8:31am
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Hello Anonymous,

Welcome to EmpowHER. Thank you for reaching out to our community with your question.

Has your gynecologist suggested weaning you off of Premarin? Thirty-two years is a long time to be on it.

For the benefit of all our readers, Premarin tablets contain conjugated estrogens, a mixture of estrogens obtained from natural sources. Estrogen is a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body.

Premarin is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Other uses include prevention of osteoporosis in postmenopausal women, and replacement of estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body.

Over the years, your doctor should have checked your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.


June 6, 2016 - 8:50am
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