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Need help. Doctor put me on progesterone therapy from a compounding pharmacy.

By February 23, 2009 - 11:03am
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Ok, so i was diagnosed with pmdd. I knew i had something because 2 weeks before my period its hell, anyway been placed on all of the depression meds you can imagine finally found the right one pristiq, the dr also wanted to check my progesterone levels and she informed me that they were low 1. This was 2 weeks before i started my period. She sent me to a compounding pharmacy and they put together progesterone. I started taking 2 weeks ago and feel ok. I also started weight watchers about 7 weeks ago and had steady loss every week. UNTIL 2 WEEKS ago, last week i gained 1.5 lbs and this week 3.5...... MY EATING HAS NOT CHANGED! I am frustrated, that is alot of weight to gain in 1 week, you would think that i was eating big macs every day. So, the question i have is, is this normal for one to gain weight on this type of med? PLEASE HELP!!!!!


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EmpowHER Guest

I think everyone reacts differently to progesterone. I recently started an oral bio identical progesterone and have lost weight, not gained. I was having a very difficult time losing weight, having a lot mood swings and basically felt terrible. My physician checked my progesterone and it was low. Since I have started the progesterone I've lost 5 pounds and feel less bloated. (Less fluid retention) I feel much better on it, and I also take a small amount of bio identical testosterone. Something else may be "off" with you, or perhaps your dosage needs to be lowered or try an oral bio identical formula. Some women are very sensitive to progesterone. Sometimes changing dosage or delivery helps.

October 6, 2016 - 10:43am
EmpowHER Guest

Please help, low vit D Low t3 possible insuline resistance have been on bio identical progesterone for 2 years, it helped me lose weight and manage my estrogen dominance until last summer when all the symptoms returned- the weight started to creep back on and I began to have rediculous pms symptoms bloating and fatigue and now am chronically dizzy. I am weening myself off progesterone per my doctors orders and now she wants to put me on metformin for insulin resistance and weight loss , but I don't know if I should take it. Has anyone been through this? Did I ruine my body? Will I have be thin and normal again. Oh yea and I eat low carb low calorie and workout 6 days a week. I am also 26 with no kids.

June 19, 2016 - 6:45pm
EmpowHER Guest

Progesterone may only be part of the problem. you need to check into Metabolic syndrome. there is a cascade of events that happen when your labs are off. I would check your cortisol level. Check your insulin levels vitamin d , and T3 and t4. Check your HgA1C. If you are insulin resistant , all the exercise in the world will not matter. You will gain weight. I am an RN and suffered for years until I finally found a doc to listen. the media is now taking note of metabolic syndrome. Let me tell you, four days after starting to correct my labs, I felt great. previously, I had the weight gain despite 1200 call ,low glycemic diet and a personal trainer. I had chronic insomnia and anxiety. As an RN , I knew I was becoming a health risk for cardiac issues. Thank God, I found someone . Metabolic Syndrome, 30-40% of the population have it. But know one is checking there patients. O by the way, the first ,
Month , I dropped 14 pounds with no change in what I was doing. In four days , my insomnia ceased. I was sleeping 1-2 hours a night for over a year. On the fouth day,I slept 14 hours. Now when I lay down, I fall fast asleep.

June 21, 2015 - 3:12pm
EmpowHER Guest
Anonymous (reply to Anonymous)

My symptoms exactly match yours! How did you treat metabolic syndrome? I exercise, run 10 miles/wk, eat pretty well but can't lose ANY weight or body fat around my waist. It is extremely frustrating!

July 30, 2016 - 6:32am
EmpowHER Guest
Anonymous (reply to Anonymous)

Hi, can you please tell me exactly what you needed to do to regulate everything again?
Something is not right and finding a doctor to listen has been a nightmare. A little about me and what I know so far. ..
I'm 34.
Periods have ceased except for a rare and very light one. This slowly started after the birth of my last child in 2008.
I have gained almost 100lbs! (Dr's just say adjust my diet)
My vitamin d was very low <5.
My testosterone levels have raised.
My cortisol was high but Dr said not an issue.
I can't sleep at night. I can literally stay up all night without ever sleeping. Not that I enjoy it but it happens a lot! Many work nights during the week I live off 2-3hrs at most each night.
Insulin levels are high.
Blood pressure is high now too.
I have no energy what so ever.
The more weight I gain the less I can even manage to workout.
I've changed diet numerous times following whatever they suggest in hopes it helps. It hasn't! I gained more!
I'm moody and lost interest in nearly everything.
Not sure if it's related to what's causing everything else or due to the weight gain and feeling angry that nothing is working.
I'm angry I want to know what is going on!
I want to have energy to play and enjoy my kids instead of feeling exhausted and irritated.
Any help is so so very appreciated!

July 11, 2016 - 3:02am
EmpowHER Guest
Anonymous (reply to Anonymous)

Hi there. You may have adrenal and/or pituitary issues. My daughter just went though many of the things you are discussing. Including dropping to 1 hour of sleep a night and gaining 60 pounds while doing P90X. Many doctors are just not familiar enough with pituitary or adrenal issues. We now go to an Internal medicine Doctor (MD) who is Holistically trained. My daughter is probably 6-8 months away from a full recover. Additionally, I would highly recommend that you get a book called the Wahl's Protocol. It is written by Terry Wahl an MD who had second progressive MS and was in a reclining wheel chair for 4 years. She studied how to heal the brain and within a year she was biking to work. Once we started our daughter on the diet, she was off all meds in a month. Including 2 controlled substances for sleep. I can't tell you what a blessing her protocol has been for us. However, you still need a doctor that is aware of auto immune diets. Her new doctor found, hopefully, the remaining missing puzzle pieces. If you are any where near Nashville TN, we highly recommend Dr. Joseph Lamb at St. Thomas Hospital. It takes 3 months to get into see him, but he is extremely thorough.

October 2, 2016 - 10:24am
EmpowHER Guest
Anonymous (reply to Anonymous)

What did your doc put you on??!

March 19, 2016 - 2:00pm
EmpowHER Guest
Anonymous (reply to Anonymous)

Hello! I would really like to know more about what interventions your doctor used to correct your issues. I think it is nearly impossible to find a good MD and would like to know more so I can talk to my doctor about options. Thank you so much!

August 7, 2015 - 6:52pm
(reply to Anonymous)

Thank you for your response. I had a saliva test done and am taking dhea, levothyroxine, progest and bi-est and test cream my acne is starting to clear and now just scars it's the puffy face hands I can't wear my wedding rings and the weight gain. I take dim , vit D ,C and b6 also on my own from my own internet searching. What did you end up doing to start losing weight?

June 22, 2015 - 5:23pm
EmpowHER Guest
Anonymous (reply to Sarahmonz)

I didn't do anything. Once I found out I had a normal glucose and elevated insulin level , everything made sense. My insulin wasn't working because , I had high cortisol, no progesterone or vitamin d and abnormal t3. I had metabolic syndrome amd was insulin wasn't working. Therefore, everything I ate got stored to fat. Even though I ate 1200 cal low glycemic index diet. Once, I found a doctor to check my cortisol, insuli, t3, t4 and started to correct them . I lost weight. You have to find a doctor who knows what metabolic syndrome is and how to treat it. If you don't correct your lab , nothing will work.

June 22, 2015 - 5:41pm
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