What to do in the combined case of hypothyroidism, galctorrhea and mastalgia?

Hello experts,
My wife is 26yrs old is suffering from hypothyroidism, glactarrohea and mastalgia. There is persistent watery/milky discharge from the right breast apart from the pain in the right breast only. The pain gets severe during menstrual cycle and slows after that which again resurfaces after heavy work. Glactorrhea and mastalgia persists even when thyroid level comes to the normal. Her breast ultrasound confirms the presence of fibroadenomas of very minute sizes in both the breast and fluid cytology confirms the benign nature and negative for any malignancy. Fibroadenomas are negligible as per surgeon, gynecologist,general physician and endocrinologist. He LSH/FH counts are normal and menses are regular and normal. Her prolactin level have been normal for past two years as tested on interval of every 4/5months. Further she has undergone the fundus test to rule out any possibility of pituitary tumor.

Her endocrinologist had administered dopamine namely bromocriptine which she responded adveresly after the very first dose. She fainted after 2 minutes of taking the dose of bromocriptine and observed sharp fall in the sugar level and low blood pressure in May 2010. In Feb2009 her gynocologist given the dopamine dose (cabergoline) to which she responded positively and the secretion of the fluid stopped for the two months to resurface again after that.

I would like to share with you that the same problem was faced by her mother in her 30s for 8-9 years which disappeared without any medication.

She has never used any medication in the past and at present not taking any drug except thryoxine. Further she has also not used any contraceptive so far. We have been married since three years. The birth is controlled partly due to abstinence and external ejaculation after short spell of penetration without condoms. So I have never used condom too. Apart from this I don't touch her both breasts for past two and half years during sex or before/after that.

Doctors have been referreing her to each other for opinion but no conclusion has been reached about the causes of pain and discharge even after two and half years of trial and error medications and diagnosis. In absence of it no medication has been administred except 2 Spells of 45 days dose of Vitamin E (Evion Cpasules), 2/3 spells of dopamine, pain killers. At present she is taking thyroxine 100mcg for last 10 days before which she was put of 50mcg dose.

One more thing I would love to share with you. 3 months before we have tried the alternative medicines of homeopathy which though didn't result into betterment of breast condition had one positive impact in lowering her pain during menses. Now she is no longer taking any homeopathy medicine.

I would like to you to advise me how to proceed next so that her pain is relieved at least. I am very upset about her pain as I love her very much. Now a days she hides her pain from me to make me happy but I can read her internal condition through her eyes expression as she is under continuous pain. On insistence she confirms my guess positively.

I have undergone lots of resarchpaper of american and british medical institutues and have found multiple opinion on this about the causes. No resarch has let me to come on a particular cause.
I would be thankful if you could take some pain to guide me about the the medicines and some measure to reduce/eliminate the pain of her breast.

Thank You
Gautam

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Tags:

• Breast Pain
• Hypothyroidism