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Hello Anonymous,
That is a very good question. Medications are a common source of acute kidney injury.
Risk factors for drug-induced nephrotoxicity are age, specifically individuals older than 60 years, underlying renal insufficiency , volume depletion, diabetes, heart failure, and sepsis.
Drugs associated with causing nephrotoxicity include:
analgesics: acetaminophen, aspirin, nonsteroidal anti-inflammatory drugs
antidepressants/mood stabilizers: Amitriptyline (Elavil*), doxepin (Zonalon), fluoxetine (Prozac),Lithium
antihistamines: Diphenhydramine (Benadryl), doxylamine (Unisom)
antimicrobials: Acyclovir (Zovirax), Aminoglycosides
I hope this was the information you are looking for.
Maryann
April 27, 2015 - 9:24amThis Comment
Great info. Can too many vitamins hurt your kidneys?
April 27, 2015 - 9:55pmThis Comment
Hello Anonymous,
By reviewing scholarly medical articles, I found an article in the Clinical Journal of the American Society of Nephrology. This is the link if you are interested in reading full article.
http://cjasn.asnjournals.org/content/2/4/757.full
"In all cases, the administration of high-dosage vitamin C (nearly 60 g/d) resulted in extensive oxalate deposition in the renal tubules with associated acute tubular necrosis. Vitamin C is metabolized to several byproducts, including oxalate, before elimination via filtration and tubular reabsorption."
Regards,
April 28, 2015 - 8:55amMaryann
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