Causes
CML is almost always associated with a gene mutation. The gene is in a chromosome called the Philadelphia chromosome. This mutation occurs during life. It is not passed from parent to child. In most cases, the cause of the mutation is not known. Studies show that exposure to large doses of radiation is associated with development of CML. This size of the dose would be found in survivors of nuclear accidents or of the atomic bomb blasts. However, most patients with the condition have not been exposed to radiation.
Risk Factors
The following factors increase your chance of developing CML:
- Sex: male
- Age: middle age or later
- Exposure to atomic bomb radiation
- Exposure to nuclear reactor accident
- Smoking
- Smoking is the only lifestyle factor that has been linked to leukemia. Its association with CML is still unclear.
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2012 EBSCO Publishing All rights reserved.
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