Creutzfeldt-Jakob Disease Causes & Risks

Causes

There has been a great deal of scientific research and debate about the cause of CJD. Today, it is generally believed that most noninherited cases are caused by infectious proteins called prions. Prions can transform normal protein molecules into abnormal, disease-causing molecules.

Risk Factors

These factors increase your chance of developing CJD. Tell your doctor if you have any of these risk factors:

Age: CJD most commonly occurs in people aged 50-75
Use of cadaveric growth hormone
Cornea transplants
Dura mater grafts
Family members with CJD (Approximately 5%-10% of cases are inherited.)
Eating beef products produced by countries with an epidemic of BSE (mad cow disease)
Healthcare workers who work with brain tissues

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2026 EBSCO Publishing All rights reserved.