Symptoms

Initially, there are no symptoms. As CJD progresses, symptoms that may occur include:

• Memory lapses
• Difficulty concentrating
• Impaired judgement
• Difficulty with speech
• Loss of coordination
• Blurred vision
• Behavior and mood changes
• Muscle spasms
• Seizures
• Loss of mental and physical function

Depending on the type of CJD, the disease may last from 3-36 months, or occasionally longer, and is almost always fatal.

Diagnosis

Your doctor will ask about your symptoms and medical history, and perform a physical exam.

CJD is a difficult disease to diagnose. There is no single test for detection. The following tests may be used to help make a diagnosis:

• Electroencephalogram (EEG) —a test that records the brain's activity by measuring electrical currents through the brain
• CT scan —a type of x-ray that uses a computer to make pictures of the inside of the body, in this case the brain
• MRI scan —a test that uses magnetic waves to make pictures of the inside of the body, in this case the brain
• Brain biopsy —removal of a sample of brain tissue for testing
• Blood tests and lumbar puncture —to obtain cerebrospinal fluid; This may be helpful in distinguishing CJD from other diseases with similar symptoms, such as Alzheimer’s disease .

MRI Scan of the Brain

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