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Neutropenia Causes & Risks

Causes

Agranulocytosis can be caused by a variety of factors, including:

  • Congenital genetic abnormality
  • Tumors, infections or other inflammations, or fibrosis of the bone marrow
  • Toxins, autoimmune diseases, infections, and other causes
  • Aplastic anemia
  • Certain medications or treatments

Risk Factors

A risk factor is something that increases your chance of getting a disease or condition. The following factors increase your chances of developing agranulocytosis. If you have any of these, tell your doctor:

  • Undergoing chemotherapy treatment for cancer
  • Taking certain drugs
  • Infection
  • Exposure to certain chemical toxins or radiation
  • Autoimmune diseases
  • Enlargement of the spleen
  • Vitamin B-12 or folate deficiency
  • Leukemia or myelodysplastic syndromes
  • Aplastic anemia or other diseases of the bone marrow
  • Family history of certain genetic diseases

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