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Causes
Agranulocytosis can be caused by a variety of factors, including:
- Congenital genetic abnormality
- Tumors, infections or other inflammations, or fibrosis of the bone marrow
- Toxins, autoimmune diseases, infections, and other causes
- Aplastic anemia
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Certain medications or treatments
- Chemotherapy treatment for cancer
- Many different drugs
Risk Factors
A risk factor is something that increases your chance of getting a disease or condition. The following factors increase your chances of developing agranulocytosis. If you have any of these, tell your doctor:
- Undergoing chemotherapy treatment for cancer
- Taking certain drugs
- Infection
- Exposure to certain chemical toxins or radiation
- Autoimmune diseases
- Enlargement of the spleen
- Vitamin B-12 or folate deficiency
- Leukemia or myelodysplastic syndromes
- Aplastic anemia or other diseases of the bone marrow
- Family history of certain genetic diseases