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Pancreatitis Causes & Risks

Causes

Causes include:

  • Alcohol abuse (most common cause)
  • Gallstones and other obstructions of the bile ducts
  • Surgery or trauma to the pancreas
  • Certain medications
  • Unknown causes (approximately 15% of cases)
  • Elevated blood triglyceride levels (hypertriglyceridemia)
  • Infections (bacterial, viral, fungal, or parasitic)
  • HIV infection
  • Congenitally abnormal pancreas duct (pancrease divisum)
  • Complication of ERCP (endoscopic retrograde cholangiopancreatography)

Risk Factors

A risk factor is something that increases your chance of getting a disease or condition.

  • Alcohol abuse
  • Family history of pancreatitis
  • Personal history of acute pancreatitis
  • Medications including:
    • Estrogens
    • Sulfonamides
    • Tetracyclines
    • Thiazides
  • Pancreatic cancer
  • Hyperlipidemia (excessive levels of fat in the blood)
  • Hypercalcemia (increased calcium in the blood)
  • Viral infections, such as mumps

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2026 EBSCO Publishing All rights reserved.

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