Causes
The exact cause is unknown. RLS may occur for no identifiable reason. This is called primary RLS. Or, it may be caused by other conditions or certain drugs. This is called secondary RLS.
Many people with RLS also have periodic limb movement disorder (PLMD). This is a related motor disorder characterized by:
- Involuntary, repetitive, jerking movements
- Interrupted sleep because of movement
Risk Factors
These factors increase your chance of developing RLS. Tell your doctor if you have any of these risk factors:
- Family members with RLS
- Pregnant—Some women have RLS during pregnancy. The symptoms usually go away after giving birth.
- Low iron levels (with or without anemia )—may happen if you give blood a lot.
- Northern European descent
-
Chronic disease (which can lead to secondary RLS):
- Peripheral neuropathy (diabetes)
- Chronic kidney failure
- Chronic venous insufficiency (varicose veins)
- Radiculopathy (nerve problem)
- Anemia
- Diabetes
- Cancer
- Chronic obstructive pulmonary disease
- Rheumatoid arthritis
- Congestive heart failure
- Certain medications (eg, tricyclic antidepressants)
- Withdrawing from certain drugs (eg, selective serotonin reuptake inhibitors [SSRIs], lithium, caffeine, dopamine antagonists, sedating antihistamines)
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2012 EBSCO Publishing All rights reserved.
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