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Early Memory Problems Linked to Heart Disease Risk Factors

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Everyone experiences them at one time or another - - temporary memory lapses. You open the refrigerator door only to forget what you wanted. Or, perhaps you lose the car keys only to find that they were in your pocket the entire time. Most of us chalk such temporary lapses up to stress or perhaps even make a few jokes about getting old. After all, isn’t memory loss just a normal part of aging? As it turns out, early memory and cognitive problems may be more than normal aging or stress. It could be a signal that you have a deeper health issue – cardiovascular disease.

Researchers with INSERM, the French National Institute of Health & Medical Research in Paris, released findings from their examination of the results of the Whitehall II study. The original Whitehall study began in 1967 and examined the cardiovascular health of more than 18,000 British civil servants. Whitehall II was a smaller study consisting of over 10,000 participants. For purposes of this study, the French researchers examined the results of 4,827 participants representing 3,486 men and 1,341 women. While the ages of participants varied, the average was 55 years.

During the course of the study, participants were given three cognition tests. The cognition tests examined participants’ responses in areas such as reasoning, fluency, vocabulary, and memory. Participants were also given a Framingham risk score for cardiovascular (heart) events. The Framingham risk score is a weighted measurement that predicts the likelihood of whether or not you’ll suffer a cardiovascular event over the next 10 years. Risk factors for heart disease such as age, high blood pressure, cholesterol levels (total and high-density lipoprotein or HDL), sex, and age are all weighted. The resulting score predicts your future susceptibility to a cardiovascular event.

Researchers found a direct correlation between the amount of cardiovascular risk and cognitive function and decline in cognitive function. Participants with the highest risk factors for heart disease were found to have much lower cognitive functions than their counterparts who were at low risk for cardiovascular events. In addition, participants with high risk for cardiovascular events also exhibited a decline in cognitive function at a greater rate than low risk participants. Researchers reported that all participants in the high risk group (10 percent or more) for cardiovascular disease scored lower on the cognitive tests. The only exceptions were in the areas of reasoning (in men only) and fluency (in women only) which did not appear impacted by the level of cardiovascular risk. Women were particularly hard hit in the area of memory. Researchers also reported that women at high risk for cardiovascular disease scored 7.1 percent lower in the area of memory while the scores for men were 2.8 percent lower than their low risk counterparts.

The findings support evidence of the link between cardiovascular health and future memory problems and cognition decline. Thankfully, cardiovascular health and your risk of developing cardiovascular disease is something which you can improve. By addressing heart risk factors which you can change (such as smoking, weight, physical activity, blood pressure, or cholesterol levels), you may not only be improving your heart health, but preventing early memory loss as well.
The study author is Sara Kaffashian, MSc. Complete study results will be presented at the American Academy of Neurology’s 63rd Annual Meeting in April, 2011.

Sources:
American Academy of Neurology (2011, February 22). High cholesterol and blood pressure in middle age tied to early memory problems. ScienceDaily. Retried February 22, 2011, from http://www.sciencedaily.com/release/2011/02/110221163047.htm
High Cholesterol and Blood Pressure in Middle Age Tied to Early Memory Problems, American Academy of Neurology, 21 Feb 2011, http://www.aan.com/press/index.cfm?fuseaction=release.view&release=907
Risk Assessment Tool for Estimating 10-year Risk of Developing Hard CHD (Myocardial Infarction and Coronary Death), National Heart, Lung & Blood Institute, http://hp2010.nhlbihin.net/atpiii/calculator.asp?usertype=prof
Jennifer Goodwin, High Cholesterol, Hypertension May Hart Memory in Middle Age, Health Day News, 2011, http://www.healthfinder.gov/news/newsstory.aspx?docID=650108

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

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