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St. John’s Wort—What is it, and Can it Really Help us Battle Depression?

 
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It’s not unusual to wake up feeling gloomy or to have days when you feel blue or unhappy about things. For many people, these feelings are temporary and often attributable to an event or situation, like a job loss or an illness. But for millions of people, feeling down is not just the symptom of some life event; it’s a very real health issue and one that often leads to a diagnosis of depression. While many people with depression are prescribed prescription medication to try to help them feel better, still others are looking for a more natural option for battling depression. For many, they have found the answer in St. John’s wort, an herbal remedy.

But does St. John’s wort really work as an anti-depressant? What is in this herbal remedy that might have such welcome healing powers, and what do the studies have to say about it?

According to About.com’s website section on alternative medicine, St. John’s wort is one of the most commonly used herbs in the United States. The plant has bright yellow flowers and because they typically bloom in late June, right around St. John the Baptist’s birthday, it was named after him. The word “wort” is Old English for “plant.”

St. John’s wort definitely has active ingredients that are responsible for whatever health benefits it may give us, but there is some question as to which ones are truly doing all of the work. Extracts of St. John’s wort are typically standardized to something called hypericin, and then another compound called hyperforin is present in the herb as well and may also help with its possible antidepressive powers. Traditionally, hypericin was thought to be the key player in St. John’s wort but more frequently, hyperforin is thought to be the primary ingredient. Other compounds in the plant that may or may have specific and positive medicinal effects include flavonoids and tannins.

One thing that is interesting about St. John’s wort is that although numerous studies have been conducted on it and its possible link to helping with depression, no one seems to know how or why the herb works. In general, the theory is that St. John’s wort may boost levels of a brain chemical called serotonin, which helps affect the emotions.

Speaking of studies, let’s move on now and look at some of the research that has been conducted on St. John’s wort and its apparent ability to help with depression. In one analysis of 27 different studies that included a total of 2,291 subjects, St. John’s wort was found to work better than a placebo in treating mild to moderate depression. It may also help us sleep better at night, which can be a major bonus for people who deal with fatigue, insomnia and/or low energy levels as side effects of their depression. St. John’s wort may also help the depression that typically goes along with chronic fatigue syndrome and seasonal affective disorder, or SAD.

References:

http://altmedicine.about.com/od/stjohnswort/a/stjohnswort.htm?p=1

http://www.wholehealthmd.com/ME2/dirmod.asp?sid=17E09E7CFFF640448FFB0B4FC1B7FEF0&nm=Reference+Library&type=AWHN_Supplements&mod=Supplements&mid=&id=21D04512184941B19F8679F8F2259EBA&tier=2

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

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