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The Diabetes-Cancer Connection

By Denise DeWitt HERWriter October 16, 2012 - 2:53pm
 
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the connection between cancer and diabetes
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Researchers have long suspected that there is a link between diabetes and cancer.

They have not been able to isolate a direct connection, and do not claim that either diabetes or cancer causes the other condition.

But they do know that if you have type 2 diabetes, you may also be at higher risk of developing cancer.

Cancer and type 2 diabetes share many of the same risk factors including:

• Being overweight

• Gender – overall, men are more likely to develop both cancer and diabetes than women

• Age – risks go up as you get older

• Race/ethnicity – African Americans and non-Hispanic whites are at higher risk of both cancer and diabetes

• Being inactive

• Smoking

• Drinking alcohol – more than one drink a day for women or two drinks a day for men increases the risk of both cancer and diabetes

Researchers suspect high levels of insulin (hyperinsulinemia) may contribute to the relationship between type 2 diabetes and cancer.

People who have type 2 diabetes develop resistance to the work of insulin, which normally acts like a key to open cells so they can take in sugar or glucose from the blood.

When insulin resistance develops, the body increases production of insulin to try to help the cells access the sugar they need for energy. This causes higher than normal levels of insulin in the body.

Insulin is also known to be active in encouraging cells to multiply, including tumor cells. So high levels of insulin in people with type 2 diabetes may be a risk factor in the development of cancer.

Little research has been done to study whether the same risk is present for people with type 1 diabetes.

If you have diabetes and also have cancer, your doctors may also face additional challenges in establishing a treatment plan to eliminate the cancer. Some treatments for cancer are known to affect blood sugar levels.

The American Diabetes Association recommends that diabetes may need to be monitored and treated more intensely to maintain safe sugar levels during cancer treatments.

For some people with type 2 diabetes, oral medications to control sugar levels may not be enough during cancer treatments.

We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

Add a Comment2 Comments

Carol Zhu

I'm not sure about other types of cancer, but i know that some diabetes medications are linked to bladder cancer. Surprisingly, this connection is only seen with newer diabetes meds, like Actos. Medications like metformin and glipizide aren't associated with bladder cancer.
http://www.publichealthwatchdog.com/generic-actos-not-worth-the-risk-rep...

October 17, 2012 - 2:44pm
Marielaina Perrone DDS Blogger

People with diabetes have so much to deal with already and then this link is there with cancer and makes it that much more difficult. But great spreading the word so patients with diabetes will be more proactive in maintaining their disease state.

Marielaina Perrone DDS
Henderson Teeth Whitening

October 17, 2012 - 9:31am
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