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Endometriosis is a painful condition resulting from the growth of endometrium (tissue lining the uterus) in other areas of a woman's body. Endometriosis can involve the fallopian tubes, the pelvic cavity and the ovaries. It can also appear in or on the bladder, bowel, cervix, rectum, vagina or vulva.
There is at present no cure for endometriosis. Treatment is primarily focused on pain relief.
According to the July 2010 issue of Obstetrics & Gynecology, from the American College of Obstetricians and Gynecologists, nonsurgical treatment should be the first line of defense against pain from endometriosis. This information was taken from an updated Practice Bulletin, "Management of Endometriosis" which contains recommendations concerning endometriosis.
Tommaso Falcone, MD, leader of the document update, suggested starting with oral contraceptives and nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs like aspirin, ibuprofen and naproxen, are analgesics which relieve pain from swelling.
If these drugs don't sufficiently relieve pain, he advised using gonadotropin-releasing hormone (GnRH) agonists or progestins. GnRH agonists cause female hormone levels to decrease which disrupts a woman's menstrual cycle and eases her pain.
Progestins stop ovulation and decrease the risk of endometriosis. This happens because progestins contain a reproductive hormone used in ovulation, called luteinizing hormone (LH).
These treatments are not advised for women who wish to become pregnant since the drugs suppress ovulation.
Hysterectomy is held in reserve as a last resort. Laparoscopic surgery uses lasers, heat or a knife to excise small amounts of endometrial tissue. An operation on a larger scale is a laparotomy which extracts tissue from the abdomen.
If a woman is not interested in having children, and if lesser treatments have not relieved her pain, her uterus may be removed. If however her ovaries are healthy and she sees children in her future, and if all the errant tissue is removed, she may be able to keep her ovaries.
This would allow for child-bearing, and would also prevent sudden-onset menopause.