Facebook Pixel

Retinitis Pigmentosa: Hereditary Loss of Vision

Rate This

Retinitis pigmentosa is a serious eye disease that is generally regarded as hereditary. It causes a gradual loss of vision over a period of years or decades, but rarely produces complete blindness. The retinal rod cells, responsible for night vision, are the most likely to be affected. The cone cells, responsible for color vision, can also be damaged in some cases. The condition gets its name from the characteristic pigmented spots on the retina.

The symptoms include:
1. Decreased vision at night or in poor light

2. Loss of peripheral vision
3. Loss of central vision in advanced cases

There is no cure at present, but research continues into therapeutic options. There are four classes of treatment in clinical trials:

1. Pharmacological. Drugs and supplements include Vitamin A, lutein, omega-3 fatty acids, hyperbaric oxygen, ciliary neurotropic factor and brimonidine tartrate
2. Gene therapy
3. Cell transplantation. This includes bone marrow derived stem cells and encapsulated cell technology implant
4. Neuro-prosthetic devices. These are also called artificial vision or retinal implants

A recent Japanese study reports that visual sensations have been produced in a blind retinitis pigmentosa patient with a surgically implanted direct optic nerve electrode. This is an important step toward development of an artificial eye system.

Researchers at USC School of Medicine in Los Angeles, Calif. report progress in an electronic prosthetic device that uses a miniature video camera mounted on eyeglasses to send visual signals to the brain. In both retinitis pigmentosa and age-related macular degeneration, the retinal photoreceptor cells lose their function, but the secondary neurons remain healthy. Second Sight Medical Products is named as the sponsor of the device furthest along in development. This company provides a web site (see references) that describes their investigational retinal prosthesis.

Volunteers are needed for clinical trials. See your eye doctor if you have a family history of retinitis pigmentosa.


Amy L. Sutton, ed, “Eye Care Sourcebook”, Omnigraphics, 2008.

Clinical trials:

Add a CommentComments

There are no comments yet. Be the first one and get the conversation started!

Enter the characters shown in the image.
By submitting this form, you agree to EmpowHER's terms of service and privacy policy

We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

Eyes & Vision

Get Email Updates

Eyes & Vision Guide

HERWriter Guide

Have a question? We're here to help. Ask the Community.


Health Newsletter

Receive the latest and greatest in women's health and wellness from EmpowHER - for free!