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Does H. Pylori Bacterium Protect Against Asthma?

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The bacterium Helicobacter pylori thrives in the stomachs of half the world’s population, according to some estimates, and that’s not necessarily a good thing as it can cause gastritis, gastric and duodenal ulcers, and stomach cancer.

But don’t attack H. pylori just yet. A July 1, 2011 article in Science Daily reported that the microorganism might actually help prevent asthma. Scientists from Switzerland and Germany who recently published their findings in the Journal of Clinical Investigation were looking in particular at allergy-induced asthma, which has increased dramatically in the industrialized world. The research came out of concern that not just air pollution and smoking are contributing to allergic diseases, but also reduced exposure to infectious bacteria through new methods of hygiene and through possible overuse of antibiotics.

If children and others are exposed to H. pylori, that might actually be a protective measure in regard to asthma, said immunologists from the University of Zurich and allergy specialists from Johannes Gutenberg University Mainz.

The normal digestive process doesn’t kill H. pylori, the article explained. If the presence of the bacteria leads to infection, there aren’t always symptoms; however, doctors concerned about gastritis and ulcers might prescribe antibiotics anyway, as a precaution. Now the debate is whether H. pylori should be left alone.

One qualifier on the possible benefits of H. pylori: when the Swiss and German researchers tested their hypothesis on mice, they found that the immunological tolerance depended on how early the mice were infected. “Early infection impairs the maturation of the dendritic cells and triggers the accumulation of regulatory T-cells that are crucial for the suppression of asthma,” said University of Zurich researcher Anne Muller. The research also looked at the outcome of giving the mice antibiotics, which caused them to lose their resistance to asthma-inducing allergens and seemed to further support the need for a careful look at the overuse of antibiotics.

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

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