Scientists Manage to Neutralize Cancer Protein

A method of neutralizing a protein believed to play an important role in leukemia and other cancers could lead to new treatments, say U.S. researchers.

The Dana-Farber Cancer Institute team made their breakthrough by examining the structure of a protein called Notch and identifying a potential weak spot. They then developed a peptide that disrupts Notch, BBC News reported.

Tests in mice showed use of the peptide limited cancer growth by reducing activity of genes both directly and indirectly controlled by Notch.

The study appears in the journal Nature.

Previous attempts at neutralizing Notch had failed, leading scientists to conclude nothing could be done to disrupt the protein, BBC News reported.

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• Leukemias
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