Antihemophilic Factor (Recombinant)

(an tee hee moe FIL ik FAK tor ree KOM be nant)

U.S. Brand Names

Advate; Helixate® FS; Kogenate® FS; Recombinate; ReFacto®

Canadian Brand Names

Helixate® FS; Kogenate®; Kogenate® FS; Recombinate; ReFacto®

Mexican Brand Names

Koate DVI; Novo Nordsk; Novoseven

Pharmacologic Category

Antihemophilic Agent

Reasons not to take this medicine

• If you have an allergy to antihemophilic factor (recombinant), mice, hamsters, pigs, or any part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

What is this medicine used for?

• This medicine is used to treat hemophilia.

• This medicine is used to prevent and treat bleeding.

How does it work?

• Antihemophilic factor (recombinant) replaces the proper proteins to prevent bleeding.

How is it best taken?

• This medicine is given as a shot into a vein.

• This medicine can be given at home.

• Your healthcare provider may teach you how to give the shot.

• Wash hands before and after use.

• Throw away needles in needle/sharp disposal box and return box to healthcare provider when full.

What are the precautions when taking this medicine?

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Short-term discomfort after use.

• Allergic reactions can rarely occur.

• Blood clots, heart attacks, and other vascular problems can rarely occur.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Follow up with healthcare provider.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Chest pain or pressure.

• Significant change in thinking clearly and logically.

• Change in strength on one side greater than the other, difficulty speaking or thinking, change in balance, or blurred vision.

• Weakness, numbness, or tingling.

• Any rash.

• No improvement in condition or feeling worse.

How should I store this medicine?

• Usually, this medicine will be given to you in a healthcare setting. You will not store it at home.

• If given at home, may store unopened vials at room temperature or in a refrigerator. Do not freeze.

• If stored at room temperature, throw away any unused Advate vials after 6 months.

• If stored at room temperature, throw away any unused Helixate® FS, Kogenate® FS, Recombinate™, or ReFacto® vials after 3 months.

• Protect from light.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.



Created: 2006-10-13 10:42:54.0

Modified: 2008-02-04 09:14:46.0

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