Interstitial cystitis is chronic inflammation of the wall of the bladder. Inflammation can lead to scarring, pinpoint bleeding of the bladder wall, and a decreased bladder capacity. Although the symptoms are similar to those of a
The symptoms of interstitial cystitis vary from person to person. They can also occur in cycles. Some people experience periods of intense symptoms followed by periods of remission. Pain can be severe enough to keep people from working or even walking.
Symptoms can include:
Discomfort, pain, or pressure in the bladder or pelvic area when the bladder is full and relief when the bladder is emptied
Urgent need to urinate
Frequent need to urinate (up to 60 times per day in severe cases)
Nocturia (urination at night, especially when excessive) from once to over 12 times every night
Your doctor will ask about your symptoms and medical history, and perform a physical exam. In addition, your urine will be tested for pus and bacteria. If bacteria are present in the urine, you will likely be diagnosed with acute cystitis—a typical bladder infection. If no bacteria are present, your doctor will likely do other tests.
A diagnosis of interstitial cystitis will only be made after other conditions have been ruled out and a
with bladder distention has been done. This consists of distending (stretching) the bladder to its full capacity by instilling liquids through the cystoscope. If interstitial cystitis is present, there will be characteristic changes in the wall of the bladder following this distension (usually called glomerulations, or occasionally Hunner's ulcers). These findings are usually interpreted as confirming a diagnosis of interstitial cystitis. Random
of the bladder might be performed if any abnormality seen.
There is no treatment to cure interstitial cystitis. Treatment is aimed at relieving symptoms. Treatment depends on your symptoms. You may have to try several different treatments before you experience relief.
Some people experience relief after the bladder distention (during the cystoscopy) is done.
During bladder instillation, a "wash" is put into the bladder through a tube in the urethra. It is held for anywhere from a few seconds to 15 minutes and then voided. There are several different types of solutions used. Some coat the bladder and are thought to decrease the inflammation. An example of this is called Hanno "cocktail," which is comprised of heparin and sodium bicarbonate.
Medications may include:
Bladder coating—taken orally to coat and protect the bladder
Antidepressants and pain relievers—for pain relief
Antihistamines—may help stop the cycle of inflammation
Antispasmodics—may alleviate frequency and urgency of urination
There is no research linking diet to interstitial cystitis. But many people find that changes in diet can help relieve pain. Different people have different "trigger" foods. Foods commonly reported to aggravate interstitial cystitis include:
TENS uses an external device that sends mild electrical impulses into the body. It has been helpful in relieving pain and decreasing frequency of urination in some people.
uses an approved device which has been reported to possibly provide symptomatic relief in some patients with interstitial cystitis refractory to more conventional treatments. This is an electronic device which is implanted into the sacral nerve roots of the spinal cord. Electrical impulses are sent to these roots in regular intervals. This is meant to modulate the neural output of the pelvic nerves supplying the bladder.
While some patients have reported some relief, they appear to be in the minority. Doctors do not know yet what makes the device helpful.
Some people are able to train their bladder to have better control by setting a regular timed schedule for emptying their bladder. The amount of time between voidings is gradually increased. Bladder training should be attempted only after pain relief has been accomplished.
Surgery is a treatment of last resort. It is used after all other treatment methods have been exhausted and if the pain remains severe. The usual approaches include either increasing the capacity of the bladder by adding a segment of bowel to the distensible portion of the bladder (ie, bladder augmentation) or by removing the entire bladder (ie, cystectomy). This surgeries are rarely done for this condition. Many people continue to have pain even after surgery.
There are no guidelines for preventing interstitial cystitis because the cause is unknown. However, recurrence or aggravation of interstitial cystitis could be reduced by avoiding the following foods or drinks:
Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the
advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a