• Clown’s Mustard
• Gastrointestinal Side Effects Caused by Medications,
Candytuft, also known as clown’s mustard, is a white flowering plant found originally in Spain. It’s a member of the Brassicaceae family, making it a relative of cabbage and broccoli. Traditionally, it was used in the treatment of arthritis, gout, enlarged heart, and asthma. The seeds, stems, roots, and leaves have all been used medicinally.
What is Candytuft Used For Today?
Candytuft is widely used in Germany for treatment of dyspepsia
Several studies, enrolling a total of over 600 participants, have found benefits for dyspepsia with use of a proprietary herbal combination therapy containing candytuft as the primary ingredient.
The product tested in these studies has undergone change over time. The original version included, along with candytuft,
Besides dyspepsia, candytuft combinations have shown potential for decreasing the gastrointestinal side effects caused by a variety of medications
What is the Scientific Evidence for Candytuft?
An 8-week, double-blind study of 315 people with functional dyspepsia tested the newer candytuft product and found it significantly more effective than placebo. 8
An earlier double-blind, placebo-controlled trial of 120 people with dyspepsia evaluated the original candytuft combination.
In another double-blind study, this one enrolling 60 people with dyspepsia, use of either the original or the newer candytuft herbal combination proved more effective than placebo.
Benefits with the original mixture were also seen in 2 other double-blind, placebo-controlled studies, enrolling a total of about 200 people.
In controlled clinical trials, use of the tested candytuft preparation has not resulted in any significant side effects. 3 Note that the studied preparation is manufactured in Germany under conditions that are more closely regulated than herbal manufacturing in the US. Formulations made outside of Germany might present unrecognized safety risks. Even with the tested product, comprehensive safety studies have not been performed. Safety for pregnant or nursing women, young children, or individuals with severe liver or kidney disease has not been established.
1. Madisch A, Melderis H, Mayr G, et al. A plant extract and its modified preparation in functional dyspepsia. Results of a double-blind placebo controlled comparative study. Z Gastroenterol . 2001;39:511-517.
2. Madisch A, Holtmann G, Mayr G, et al. Treatment of functional dyspepsia with a herbal preparation. A double-blind, randomized, placebo-controlled, multicenter trial. Digestion . 2004 [Epub ahead of print].
4. Gundermann KJ, Godehardt E, Ulbrich M. Efficacy of a herbal preparation in patients with functional dyspepsia: a meta-analysis of double-blind, randomized, clinical trials. Adv Ther . 2003;20:43-49.
7. Rosch W, Vinson B, Sassin I. A randomized clinical trial comparing the efficacy of a herbal preparation STW 5 with the prokinetic drug cisapride in patients with dysmotility type of functional dyspepesia. Z Gastroenterol . 2002;40:401-408.
8. von Arnim U, Peitz U, Vinson B, et al. STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study. Am J Gastroenterol. 2007;102:1268-1275.
Last reviewed April 2009 by EBSCO CAM Review Board
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