Certain Anti-Depressants May Be Effective for Severe PMS Symptoms
A team of researchers conducted a review of numerous past studies of severe PMS treatment. Their goal was to find the effectiveness of a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). The review found that this type of drug was effective in reducing severe PMS symptoms.
About the Study
- Overall intensity of symptoms
- Behavioral symptoms (eg, mood changes, irritability)
- Physical symptoms (eg, fatigue, cramping)
- Functional symptoms (eg, problems in social and work life)
There were some side effects associated with SSRIs. The groups that received the medication did report higher rates of nausea,
How Does This Affect You?
Severe PMS interferes significantly with daily activities. Pain, troublesome mood changes, and overwhelming fatigue make it difficult to get through the day. Fortunately, SSRIs seem to be effective at relieving these symptoms for many women. Since these medications all require a prescription and are not without side effects, speak to your doctor about how best to manage your severe PMS symptoms.
American College of Obstetricians and Gynecologists
National Women's Health Resource Center
Brown J, O'Brien PMS, Marjoribanks J, Wyatt K. Selective serotonin reuptake inhibitors for premenstrual syndrome. Cochrane Database of Systematic Reviews. 2002, Issue 3. Art. No.: CD001396. DOI: 10.1002/14651858.CD001396.
Last reviewed April 2009 by
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