. Cancer is the uncontrolled division and growth of cells. As the cancer cells grow, they crowd out healthy cells and interfere with normal body processes. In most cases, the cell growth forms a mass (ie, tumor). However, IBC cells grow in more of a sheet-like shape.
IBC is an aggressive form of cancer that can be hard to detect. It may look like
, which is simply inflammation of the breast. Early diagnosis and treatment are important. The sooner treatment is started for IBC, the more favorable the outcome.
Breast Changes Associated With IBC
Skin changes that resemble the skin of an orange and/or inversion of the nipple may be signs of IBC.
Note: Studies show that most women with known risk factors do not get breast cancer. Many women who get breast cancer have none of the risk factors listed above.
If you have any of these symptoms, do not assume it is due to IBC. These symptoms may be caused by other conditions. As the IBC cells get into the skin and lymph ducts they may cause signs and symptoms such as:
Rapid change in the size, shape, or feel of one breast (can occur over days or weeks)
Discoloration of the breast; breast may appear red, purple, pink, or bruised
An area of the breast that looks like the skin of an orange
Thickened areas of skin
Breast feels warm to the touch
Changes in the nipple, such as flattening, turning in, retracting, or areola color change
Enlarged lymph nodes under the arm or above or below the collarbone
Some of these symptoms are similar to a condition known as
. However, mastitis should respond to
. If it does not, talk to your doctor again right away.
Your doctor will ask about your symptoms and medical history. A physical exam will also be done. Since IBC develops in a sheet-like pattern instead of lumps, it is hard to find by a breast exam or
If your doctor suspects IBC, she may order:
(excisional or skin)—a sample of tissue is removed and examined for cancer cells
—to look for any sign of the cancer outside of the breast
If cancer is detected, the cancerous tissue will also be tested to look for:
HER2 gene—suggests an aggressive form of cancer
Cancer treatments vary from person to person. Talk with your doctor about the best plan for you. The goal is to treat the IBC locally and to prevent it from spreading and recurring. Common treatment options include the following:
is the use of drugs to kill cancer cells. It may be given in many forms including pill, injection, and via a catheter. The drugs travel through the body in the blood, killing mostly cancer cells. Some healthy cells are killed as well. Chemotherapy drugs for IBC may include:
The timing of surgery can be an important factor in the outcome. Surgical options may include:
(may also be called tylectomy or quadrantectomy)—removal of the breast cancer and some normal tissue around it (Often, some of the lymph nodes under the arm are also removed.)
Segmentectomy—removal of the cancer and a larger area of normal breast tissue around it
—removal of the breast, or as much of the breast as possible (The surgeon will try not to remove lymph nodes.)
Radical mastectomy—removal of the breast, chest muscles, the lymph nodes under the arm, and some additional fat and skin (This procedure is only considered in rare cases. It is done if the cancer is found in the chest muscles.)
Modified radical mastectomy—removal of the whole breast, the lymph nodes under the arm and, often, the lining over the chest muscles
Some surgical procedures may also be done to determine if the cancer has spread:
Axillary lymph node dissection—removal of the lymph nodes under the arm (This will help find any cancer cells that have entered the lymphatic system.)
is the use of radiation to kill cancer cells. Two main types of radiation may be used:
External radiation therapy—radiation directed at the breast from a source outside the body
Internal radiation therapy—radioactive materials placed into the breast in or near the cancer cells
There are other factors about your specific type of cancer that can affect treatment such as:
Hormone receptors—some cancers have hormone receptors attached to them. Certain drugs can target these receptors to help control or eliminate the cancer. This hormone therapy may include drugs such as:
It is important to catch IBC as early as possible. If you have any of the symptoms listed above, see your doctor right away. If you are being treated for mastitis that is not responding to treatment, see your doctor again.
Breast exams may help identify changes in your breast such as the “orange-peel skin” effect. For breast exams, the
American Cancer Society
Women aged 20 or older may perform a
(BSE) every month. Report any changes to your doctor right away.
Women aged 20-39 should have a clinical breast exam by a health professional every three years. Starting at age 40, women should have a clinical breast exam every year.
A breast exam should be done more regularly if there is a family history or there have been previous breast biopsies.
Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the
advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a