Immunotherapy is often recommended for people who have developed severe side effects from medication, or when symptoms do not respond well to medication. Allergy shots may also be helpful for people who have frequent, unavoidable exposure to allergens. Studies have shown that immunotherapy is effective in 80%-90% of people who receive this treatment on a consistent basis.
Immunotherapy is an asthma treatment consideration for those whose asthma is exacerbated by allergens (like animal dander), rather than other triggers like viral respiratory infections.
Immunotherapy increases your resistance to your allergens and reduces the need for medications. Initially, you will be given shots of weakened solutions of purified allergen extracts 1-2 times per week. As you continue with the shots, the doses will be made progressively stronger. In approximately 5-6 months, your doses will be at the most concentrated, or maintenance, level.
Once your injections are at maintenance level, the frequency of injections will be reduced to every 2-4 weeks. Your healthcare provider will monitor your immune response periodically by skin testing. Treatment will continue for about 2-5 years until your allergic response has been significantly reduced or eliminated.
Immunotherapy is a treatment program that may take 2-5 years to complete. If you are considering this form of treatment, you will need to make a commitment to receive these injections on a regular schedule. If you miss one or more treatments, there is a risk that your allergen immunity will be compromised, and you may need to begin the process again.
On occasion, some people experience a localized reaction to the shot, which may consist of itching, redness, or a small swelling in the injection area. These symptoms usually disappear within 1-2 hours.
In very rare instances, a systemic reaction may occur. This might produce symptoms such as sneezing; itching of the eyes, throat, hands, or feet; or asthma. This type of reaction usually occurs within twenty minutes of the shot. Your doctor will have you wait at least 20 minutes after receiving an injection to assure that there is no reaction.
Who Should NOT Undergo Immunotherapy
Immunotherapy is not recommended for people who are taking beta-blocker medications. Beta-blocker medications may be prescribed for people who have high blood pressure, heart rhythm problems, or other conditions.
It has not been conclusively determined whether starting immunotherapy is safe during pregnancy. However, it is usually considered safe to continue immunotherapy maintenance treatments during pregnancy as long as it’s approved by your doctor.
Immunotherapy is also not recommended for people with weakened immune systems.
When to Contact Your Doctor
Notify your doctor immediately if you notice:
Any changes in your allergy reaction—either after an allergy shot or in general
Any adverse reactions to the injection
Any changes in medications prescribed by another doctor
American College of Allergy, Asthma, & Immunology
website. Available at:
Accessed July, 2008.
Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the
advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a