Begin taking an antibiotic if advised by your doctor.
Use an enema several hours before the procedure.
If you will be getting general anesthesia, do not eat or drink anything after midnight.
This depends on the method that your doctor uses:
Transurethral biopsy and perineal biopsy:
General anesthesia—blocks pain and keeps you asleep through the surgery, given through an IV in your hand or arm
Local anesthesia—just the area that is being operated on is numbed, given as an injection and may also be given with a sedative
Transrectal prostate biopsy—local anesthesia
Description of the Procedure
Your doctor will use one of the following methods to do the biopsy:
Transrectal biopsy (most common method)—Your doctor will insert a small ultrasound device into the rectum. This device will emit sound waves to produce an image of the prostate. These images will help guide placement of the needle. Your doctor will then insert the needle through the wall of your rectum and into the prostate gland.
Transurethral biopsy—Your doctor will insert a lighted flexible tube through the penis into the urethra. The urethra carries urine from the bladder. Your doctor will get the biopsy with a cutting loop that is passed through the flexible tube.
Perineal biopsy—Your doctor will make a small incision in the perineum. The perineum is the area between the scrotum and the rectum. The doctor will insert a small needle into the prostate gland to get the biopsy.
How Long Will It Take?
About 30 minutes
Will It Hurt?
You may have discomfort and soreness at the biopsy site.
When you return home after the procedure, do the following to help ensure a smooth recovery:
Stay hydrated. Drink plenty of fluids for the next few days.
Avoid strenuous activity the day and evening of the procedure.
Keep in mind that you may see blood in your urine, stool, or ejaculate for several days.
Ask your doctor when you can resume taking your blood-thinning medicine.
Be sure to follow your doctor's
Once the sample is taken, it will be sent to a pathologist. This doctor will analyze the sample for cancer. If cancer is present, your doctor will work with you to develop a treatment plan.
Call Your Doctor
After arriving home, contact your doctor if any of the following occurs:
Inability to urinate
Blood in the urine more than 2-3 days post-biopsy
Signs of infection, including fever and chills
Pain that you cannot control with the medicines you have been given
Pain, burning, urgency, or frequency of urination
Cough, shortness of breath, or chest pain
Persistent rectal bleeding or scant rectal bleeding that lasts more than 2-3 days after the biopsy
Rodriguez LV, Terris MK. Risks and complications of transrectal ultrasound guided prostate needle biopsy: a prospective study and review of the literature.
J Urol. 1998;160(6-I):2115-2120.
Tiong HY, Liew LC, Samuel M, Consigliere D, Esuvaranathan K. A meta-analysis of local anesthesia for transrectal ultrasound-guided biopsy of the prostate. Prostate Cancer Prostatic Dis. 2007;10(2):127-36. Epub 2007 Jan 9.
Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the
advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a