Risk Factors for Type 1 Diabetes
A risk factor is something that increases your likelihood of getting a disease or condition. It is possible to develop
If you have a parent, brother, or sister with type 1 diabetes, you (or your child) are at greater risk of having it, too. Scientists continue to believe that genetic factors play a role in the development of type 1 diabetes.
Type 1 diabetes is an autoimmune disease, caused by the body's immune system attacking the insulin-producing cells of the pancreas. You may be at a greater risk of developing type 1 diabetes if you have another condition that affects the immune system, such as:
You are at an increased risk of type 1 diabetes if your ethnicity is:
- Northern European
- African American
Presence of Islet Cell Antibodies
Through lab tests, your doctor can determine if you have islet cell antibodies. These are a type of antibodies that destroy the insulin producing part of the pancreas. Having these antibodies may increase your chance of developing type 1 diabetes.
Other Risk Factors
Other factors that may increase your child's risk of type 1 diabetes include:
- Bottle-feeding or short duration of breastfeeding
- High birth weight
- Mothers age at childbirth (over 35 years)
American Diabetes Association website. Available at: http://www.diabetes.org/home.jsp .
Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov .
Medical conditions. Diabetes: type 1. Risk factors. University of California Davis Health Center website. Available at: http://www.ucdmc.ucdavis.edu. Accessed October 19, 2004.
Schatz D, Krischer J, Horne G, et al. Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives. J Clin Invest. 1994;93:2403-2407.
TRIGR study: a new trial investigates environmental triggers in type 1 diabetes [press release]. Juvenile Diabetes Research Foundation International website. Available at: http://www.jdrf.org. August 7, 2002. Accessed October 19, 2004.
3/12/2010 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php: Cardwell CR, Stene LC, Joner G, et al. Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data. Diabetologia. 2010 Jan 10. [Epub ahead of print]
3/12/2010 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php: Cardwell CR, Stene LC, Joner G, et al. Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studies. Diabetes. 2010;59(2):486-494.
Last reviewed December 2009 by
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