Tourette syndrome (TS) is a chronic, neurological disorder that is a member of a larger group of primary tic disorders. It is characterized by motor and vocal tics. Both motor and vocal tics must be present, though not necessarily at the same time. Tics must be present for more than one year, and its onset must be prior to age 18. Tics are rapid, involuntary movements or sounds that occur repeatedly.
In most cases, TS is inherited through a gene (or genes). However, some patients may have milder tic disorders or
symptoms with no tics. Sometimes there are no symptoms.
Some people with TS have no known family history of TS, tics, or obsessive-compulsive symptoms. Researchers are studying whether other factors, such as birth-related issues and autoimmune problems, may contribute to TS.
TS is one of the conditions grouped under the category Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal (or PANDAS). Studies suggests that, in some children, PANDAS are associated with Group A streptococcal or
Researchers are studying whether the risk of PANDAS can be decreased by rapid treatment or prevention of strep infections. Also, studies need to be done to find out if some children are at a higher risk because of their genetic make-up. Overall, strep infection is common. So, if PANDAS are caused by the infection, then it's likely to occur only rarely.
Other than this possible connection, the cause of tics is unknown. However, studies show that several brain chemicals, called neurotransmitters, are involved. Dopamine and serotonin are most likely involved. In addition, stress and tension often increase tics.
Tell your doctor if you have any of these risk factors:
Family history of TS, other tic disorders, or obsessive-compulsive disorder
Sex: male (three to four times more likely to be affected)
(may be a risk in some children)
There are many secondary causes of tics including:
Symptoms range from mild to severe, but most cases are mild. They can occur suddenly, and the length of time they last can vary. Tics may temporarily decrease with concentration or distraction. During times of stress, they may occur more often.
Tics are divided into motor and vocal, and then subdivided into simple and complex. The following are common examples:
Simple—eye blinking, facial grimacing, head jerking, arm or leg thrusting
Complex—jumping, smelling, touching things or other people, twirling around
While tics may occur throughout life, older teens may find that symptoms improve. In less than 10%-40% of cases, people have remission from symptoms.
The doctor will ask about your symptoms and medical history, and perform a physical exam. TS is diagnosed by observing the symptoms and reviewing when they began and how they progressed. There are no blood or neurological tests to diagnose TS. Some doctors may order an
, or blood tests to rule out other disorders.
Most people with TS do not need medical treatment.
If you have a tic that disrupts daily activities, there are treatments. The most common is medication.
No single treatment is helpful for all people with TS. Treatment may not completely eliminate symptoms.
Several medications can help control tics, including:
Behavior therapy can help people with TS learn to substitute their tics with other movements or sounds that are more acceptable.
Cognitive behavioral therapy can help reduce obsessive-compulsive symptoms.
Relaxation, biofeedback, and exercise can reduce the stress that often makes symptoms worse.
Psychotherapy can help people with TS and their families cope with the disorder. In tic disorders associated with PANDAS,
intravenous immunoglobulin therapy
has been used with some success in a small number of patients, but is still considered experimental.
Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the
advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a