The treatment and management of cold sores involves medications and lifestyle changes.

Although treatment can help relieve or reduce outbreaks of cold sores, they cannot be permanently cured. Herpes simplex virus 1 will persist in the nerve tissue once it is infected. Therefore, treatment is focused on preventing cold sore outbreaks and reducing the severity of symptoms.

Treatment involves the following:

Lifestyle changes
Medications
Alternative and complementary therapies

There are no surgical options for the treatment of cold sores.