If you have been diagnosed with mucormycosis, you may wish to ask your physician these additional five questions:
1. What line of treatment will you recommend for me?
Mucormycosis’ treatment is an aggressive one due to its disseminating nature within the body. The following treatment protocols are generally followed in case mucormycosis is suspected and diagnosed:
a. Doctors usually start with an intravenous injection of a strong dose of Amphotericin B. Dosage and potency is determined by the physicians and specialists. They could use a 1-1.5mg per kg IV infused in 5 percent dextrose over four to six hours measure. Amphotericin B in Phospholipid Complex form of the drug with a dosage of 5 mg per kg/d IV is also an alternative/choice. Pediatric doses are suggested by physicians.
b. At times Posaconazole is used in place of Amphotericin B. The potency and dosage are prescribed by the doctors generally following the rule of 800 mg/d in two to four equally-divided doses with food or supplements.
c. Both drugs have side effects in mid-long term treatment and the doctors will go through your case depending on your medical case history.
d. Drainage and lavage of sinuses
2. Will I have to undergo any surgical procedures?
That depends upon further testing of your lung to confirm the extent and stage of mucormycosis you have. If required, you will have to undergo a surgery, which may involve surgical removal of fungal balls and dead or infected tissues after following a complete course of either Amphotericin B or Posaconazole. This has the potential of disfiguring the eye, nasal and palate cavities and a restorative surgery would later be recommended. Avoiding surgery could lead to relapse/recurrence and death.
3. Do I need to worry about anything before the surgery?
Before surgery is undertaken, certain key points must be taken care of and observed. They are:
• Ceasing any immunosuppressant drugs such as steroids before surgery.
• Interrupting any deferoxamine therapy if being given.
• Diabetic ketoacidosis requires insulin, correction of acidosis with sodium bicarbonate, and rehydration.