FRIDAY, Dec. 4 (HealthDay News) -- Cancer patients, glaucoma patients and others can benefit from medical marijuana, and now a new analysis shows that it can help multiple sclerosis (MS) patients find relief from the muscle spasms that are the hallmark of the debilitating autoimmune disease.
"The therapeutic potential of cannabinoids in MS appears to be comprehensive, and should be given considerable attention," said lead researcher Dr. Shaheen Lakhan, executive director of the Global Neuroscience Initiative Foundation.
"Spasticity, an involuntary increase in muscle tone or rapid muscle contractions, is one of the more common and distressing symptoms of MS," the researchers noted in their review. "Medicinal treatment may reduce spasticity, but may also be ineffective, difficult to obtain or associated with intolerable side effects," they added.
"We found evidence that cannabis plant extracts may provide therapeutic benefit for MS spasticity symptoms," Lakhan said.
Although some objective measures showed improvement, there were no significant changes in after-treatment assessments, Lakhan said. "However, subjective assessment of symptom relief did often show significant improvement post-treatment," he added.
For the study, Lakhan and his colleague Marie Rowland reviewed six studies where marijuana was used by MS patients. Five of the trials showed that marijuana reduced spasms and improved mobility, according to the report published Dec. 3 in the online journal BMC Neurology.
Specifically, the studies evaluated the cannabis extracts delta9-tetrahydrocannabinol (THC) and cannabidiol (CBD). These studies found that both THC and CBD extracts may provide therapeutic benefit for MS spasticity symptoms, Lakhan said.
Although there was a benefit from using marijuana there were also side effects, such as intoxication. This varied depending on the amount of marijuana needed to effectively limit spasms, but side effects were also seen in the placebo groups, Lakhan and Rowland noted.
The careful monitoring of symptom relief and side effects is critical in reaching an individual's optimal dose, Lakhan said.
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