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Genetic Data May Predict Colon Cancer Odds

Genetic Data May Predict Colon Cancer Odds

January 16, 2009 - 12:19pm 123 reads 0 comments

FRIDAY, Jan. 16 (HealthDay News) -- Areas of deleted genetic data in key DNA may prove to be a biomarker that predicts whether a person will develop colon cancer, a new study finds.

These "hot spots" in the AMACR gene, found in human tissue, may also show how aggressive the cancer could be, according to the report in the Jan. 16 issue of PLoS Genetics.

"From the colon tissues, we've identified two types of genetic deletions that may allow us to predict whether people will have a good or bad cancer outcome," study first author Xiang Zhang, a University of Cincinnati environmental health research associate, said in a news release issued by the school. "If a person carries one of the deletions, it may predispose him or her to a more aggressive type of colon cancer."

AMACR breaks down certain fatty acids (known as "branch chained") that are found only in plant-eating animals. Red meat and dairy products, then, can contain these plant-derived fatty acids, which can hasten cancer development and growth, previous research has found.

The researchers said that such genetic findings could assist people in making healthier lifestyle choices.

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