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Genetic Test for Heart Disease Risk in the Works

Genetic Test for Heart Disease Risk in the Works

February 8, 2009 - 4:43pm 169 reads 0 comments

SUNDAY, Feb. 8 (HealthDay News) -- Perhaps five years from now, you might actually hear your doctor casually say, "While we're at it, let's do a blood test to see if your genetic makeup puts you at high risk of having a heart attack."

So says Dr. Sekar Kathiresan, an assistant professor of medicine at Harvard Medical School and director of preventive cardiology at Massachusetts General Hospital. He is the leader of a group that has identified three new genetic variants associated with an increased risk of heart attack.

That finding, which brings the total of such risk-associated variants to nine, is reported in the Feb. 8 online issue of Nature Genetics. The journal highlights a total of five papers from groups around the world looking at the genetics of heart disease.

The study led by Kathiresan, done by a group of six organizations called the Myocardial Infarction Genetics Consortium, is the largest of the five. It compared the genomes of about 3,000 people who had suffered heart attacks relatively early in life -- under 50 in men, under 60 in women -- with those of 3,000 people who hadn't had a heart attack.

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