Clues to Alzheimer's Spotted Earlier in Disease
WEDNESDAY, June 24 (HealthDay News) -- Biomarkers for Alzheimer's disease can be detected in the cerebrospinal fluid in the very early stages of the disease, a Swedish study suggests.
University of Gothenburg researchers analyzed cerebrospinal fluid (CSF) samples from 168 patients and found the typical pattern of biomarkers known as the "CSF AD profile" present in patients with mild memory problems, which is earlier than the illness could be detected by current tests.
"The earlier we can catch Alzheimer's disease, the more we can do for the patient," researcher Kaj Blennow said in a university news release. "The patients who had the typical changes in biomarker profile of the cerebrospinal fluid had a risk of deterioration that was 27 times higher than the control group. We could also see that all patients with mild cognitive impairment who deteriorated and developed Alzheimer's disease had these changes in the biomarker profile of their cerebrospinal fluid."
The study also found a relationship between the CFS AD profile and other typical signs of Alzheimer's, including the presence of the gene APOE e4 and deterioration of the area of the brain that controls memory.
Add A New Comment
Add A New CommentComments
There are no comments yet. Be the first to get the conversation started.