Possible Gene Regions for Schizophrenia Located
This was done in order to exclude numerous non-disease-related genetic differences that would have to be sorted through if participants had different ancestries.
The researchers used the latest genetic technologies to search for tiny genetic variations called single base-pair polymorphisms (SNPs). They found that the largest genetic differences between people with schizophrenia and those without the disease were found on chromosome 6.
The findings are presented in three papers published online July 1 in the journal Nature. "The papers present the first highly significant findings of gene regions associated with schizophrenia risk," Levinson said.
He added that "these findings show that our genetic methods are working and that the genetic underpinnings of schizophrenia can be understood. Similar methods have produced critical new discoveries in many other common diseases, once very large numbers of people could be studied. Now we see that the same approach works for psychiatric disorders like schizophrenia."
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