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Non-AIDS-Related Cancers Growing Among HIV Patients

Non-AIDS-Related Cancers Growing Among HIV Patients

September 30, 2009 - 12:35pm 275 reads 0 comments

WEDNESDAY, Sept. 30 (HealthDay News) -- Non-AIDS-related cancers such as anal and lung cancer have become more common among HIV patients than among people without HIV since antiretroviral therapies were introduced in the mid-1990s to treat people with the virus, U.S. researchers say.

Because of their weakened immune system, AIDS patients are at increased risk for so-called AIDS-defining malignancies, which include cancers such as cervical carcinoma, non-Hodgkin's lymphoma and Kaposi's sarcoma.

There has been speculation that non-AIDS-defining malignancies are becoming more common among HIV patients because antiretroviral drugs help them live longer. But this new study by researchers at University of Texas Southwestern Medical Center in Dallas suggests other factors may exist.

The researchers analyzed 1997 to 2004 data from more than 100,000 patients in the U.S. Veterans Affairs Healthcare System and found that HIV-infected patients were 60 percent more likely to have anal, lung, Hodgkin's, melanoma or liver cancer than patients without HIV.

"It's a genuine increase in the incidence of these cancers," lead author Dr. Roger Bedimo, an assistant professor of internal medicine, said in a university news release.

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