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Phosphate: Silent, Stealthy Killer

September 7, 2009 - 5:40am 606 reads 4 comments

Phosphate is not poisonous unless something is wrong. Our bones and teeth are composed primarily of calcium phosphate. Healthy levels of phosphate in the bloodstream and tissues are vital to our metabolism. But too much dissolved phosphate is linked to death from cardiovascular disease.

My doctor routinely orders blood tests for lipids (cholesterol and triglycerides), liver function, blood count, and the basic metabolic profile of glucose, blood urea nitrogen (BUN), creatinine, sodium, potassium, chloride, carbon dioxide, and calcium. Phosphate is not included; I've never had my phosphate checked. So the first reference for this article caught my attention.

Phosphate, according to the medical literature, is a key factor in atherosclerosis. Experiments with animal models and human aorta cell cultures indicate that elevated phosphate in the blood tricks artery cells into acting like bone-producing cells (osteoblasts). These artery cells produce mineral deposits, which form calcified plaques. As Reference 1 describes the process, hyperphosphatemia (too much phosphate in the blood) is “an 'insidious bone-maker' in the walls of blood vessels”. For me, this puts “hardening of the arteries” in a new perspective.

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Anonymous

This is new news to me! Thank you, Linda, for bringing this to my attention!

Mary Kyle

Hi Linda... This was news to me as well. I've never even had a doctor mention phosphate and cholesterol or heart disease in the same conversation. For that matter, I don't think I've ever heard my doctor mention phosphates to me and I know I've never had my levels tested. I'll discuss with him the next time I go in!

For those interested in knowing if they already have plaque forming in their arteries, there is a preventative diagnostic test that may be of interest. CT Heart Scans are being used quite a bit in our region in cases where people have high risk factors to determine if heart disease has begun. You can read more info at the link below. Again, THANKS for providing such great info!
http://www.empowher.com/news/herarticle/2009/08/31/woman%E2%80%99s-heart...

Mary Kyle

Hi Linda... This was news to me as well. I've never even had a doctor mention phosphate and cholesterol or heart disease in the same conversation. For that matter, I don't think I've ever heard my doctor mention phosphates to me and I know I've never had my levels tested. I'll discuss with him the next time I go in!

For those interested in knowing if they already have plaque forming in their arteries, there is a preventative diagnostic test that may be of interest. CT Heart Scans are being used quite a bit in our region in cases where people have high risk factors to determine if heart disease has begun. You can read more info at the link below. Again, THANKS for providing such great info!
http://www.empowher.com/news/herarticle/2009/08/31/woman%E2%80%99s-heart...

Linda Fugate

The latest news on kidney failure is the prevalence of selling human kidneys for transplants. See http://www.empowher.com/news/herarticle/2009/09/14/transplant-kidneys-sale
Let's get those checkups and try to reduce the demand for kidney transplants!

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