Recurrent Urinary Tract Infection Linked to Immune Defects and Vaginal Infections
Many women get only one urinary tract infection (UTI) in their lifetime, but others get repeat episodes. Recurrent UTI is associated with inflammatory diseases such as rheumatoid arthritis and type 1 diabetes. Vaginal infections, especially bacterial vaginosis, are also associated with UTI. What makes some women susceptible?
A research team based in Canada wants to find out. For their initial study, they identified 22 women with recurrent UTI and 17 healthy controls. They examined blood, urine, and vaginal samples taken at a time when each subject was free of UTI symptoms. Their findings include significant differences between the immune system characteristics and vaginal flora of women with and without recurrent UTI.
Genetic differences appear to be part of the problem. A family history of UTI is a risk factor, and the blood tests showed abnormalities in the immune systems of women with recurrent UTI. These women may have a chronic, low-grade infection. When the symptoms of UTI return, they are typically caused by the same strain of bacteria. Chronic infection is associated with chronic inflammation, which can explain the association with rheumatoid arthritis and type 1 diabetes.
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Linda - Anyone who's had a urinary tract infection knows they're no fun, and recurrent ones can be a major problem. It's good to know that studies are underway to learn more about the causes which will no doubt help many women. Thanks for providing this important information.
Take good care,
Pat