Greetings Sisters. I am 56 years old, hysterectomy done at age 39 and have been taking estrogen (estrace or estradiol) for 17 years. Whenever I try to decrease or eliminate the therapy, hot flashes, night sweats, insomnia, etc is so bad I just go right back to therapy again. I am currently taking 1 mg tablets estradiol 4 days a week and .05 mg 3 days a week. Still getting some hot flashes and night sweats but it is not debilitating. Does anyone have a similar history or thoughts on switching to Amberen? Thanks in advance. Naner