Blood poisoning is an illness due to an infection or its toxin spreading through the bloodstream. The presence of bacteria in the blood is called bacteremia.
Short bursts of low levels of bacteria in the blood usually do not cause problems. If bacteria continue they may cause sepsis. This is a serious condition which can lead to death.
Sepsis occurs when large numbers of infectious agents exist in the blood. Infections with fungi and parasites may lead to sepsis as well. The initial infection often comes from:
Bacteria can also enter the bloodstream directly from an outside source. A dirty needle used by an IV drug user can cause this type of infection. In some cases, the source of the infection is unknown.
Small amounts of bacteria enter into the blood with dental work or when brushing your teeth. Your body's immune system should fight off these bacteria.
These factors increase your chance of getting sepsis:
The first symptoms depend on the site of the infection.
As the condition progresses to sepsis, symptoms include:
The doctor will ask about your symptoms and medical history. A physical exam will be done. If sepsis is suspected, the doctor will try to find the source of the infection.
Tests include:
This condition will need to be treated aggressively. Treatment is aimed at the cause of the initial infection.
Early treatment improves the chance of survival. Life-saving steps may be needed to assist breathing and heart function. Patients usually need to be observed in an intensive care unit.
IV antibiotics will be used to fight the initial infection and to clear it out of your blood. You will be given oral antibiotics when you leave the hospital.
Surgery is sometimes needed to remove or drain the initial infection.
You will likely receive other medications, IV fluids, and oxygen. Blood transfusions and a respirator (to help you breathe) may be necessary in some cases. Further treatment depends on how your body is responding. For example, you may need kidney dialysis if kidney failure occurs.
RESOURCES:
National Center for Infectious Diseases, Centers for Disease Control and Prevention
http://www.cdc.gov/
Society of Critical Care Medicine
http://www.sccm.org/
CANADIAN RESOURCES:
Communicable Disease Control Unit (Manitoba Health, Public Health Branch)
http://www.gov.mb.ca/
Health Canada
http://www.hc-sc.gc.ca/
References:
Bone RC. Pulmonary & Critical Care Medicine . 1998 ed. St. Louis, MO:Mosby-Year Book, Inc.;1998.
Cecil RL, Goldman L, Bennett JC. Cecil Textbook of Medicine . 21st ed. Philadelphia, PA:WB Saunders Company;2000.
Conn HF, Rakel R. Conn's Current Therapy 2001 . 53rd ed. Philadelphia, PA:WB Saunders Company;2001.
Kasper DL, Harrison TR. Harrison’s Principles of Internal Medicine . 17th ed. New York, NY:McGraw Hill;2008.
Mandell GL, Douglas RG, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases . 5th ed. Philadelphia, PA:Churchill Livingstone, Inc.;2000.
Last reviewed September 2009 by Igor Puzanov, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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